江西省人民医院神经内科登上复旦声誉榜、医信天下百强榜

作为评估中国医院学科建设水平的标杆之一,复旦版中国医院排行榜,在2020年12月份揭榜。江西省人民医院在2019年度华东区神经内科声誉排行榜上获提名。同时神经内科在医信天下2020中国医院影响力神经内科排行榜同等53名。



  复旦大学医院管理研究所在上海颁布《2019年度中国医院排行榜》、《2019年度中国医院专科声誉排行榜》和《2019年中国医院专科综合排行榜》,这是复旦大学医院管理研究所作为独立第三方开展的公益性学科评估项目,已是复旦版中国医院排行榜连续第十一年发布。
  在成为中国医院学科建设的一个标杆同时,该榜单也常常被作为大众疑难杂症寻找心中好医院的重要参考。根据排行榜,该榜单由复旦大学医院管理研究所发布,借鉴美国“最佳医院排行榜”的评价方法,坚持以临床学科水平、专科声誉为核心,兼顾当年的科研产出。由于评价方法的科学性,排行榜的评选结果亦得到医疗行业广泛认可。
  我院神经内科在全国神经病学中占有一席之地,离不开江西省卫健委的正确指引和院领导的大力支持。学科建设是医院发展的重中之重,是医院品牌、声誉、地位的基石,是医院增进绩效、合理分配、吸引人才的基础,也是医院加强管理、提高质量、发展医学的抓手。
 
  江西省人民医院神经内科简介
 
  江西省人民医院(南昌大学附属人民医院)神经内科是江西省唯一卫生部认定的国家临床重点专科(神经内科专业),国家高级卒中中心,国家卫健委指定的脑卒中筛查与防治基地,国家卫健委指定的临床路径试点单位,国家住院医师规范化培训神经内科专业基地,国家药物临床实验机构,国家神经变性病联盟高级中心,华南神经系统线粒体病协作联盟,中华医学会神经病学分会委员单位,江西省医学会神经病学分会主委单位,江西省保健学会神经病学分会和睡眠医学分会主委单位。是江西省神经内科专业质量控制中心、江西省神经系统疾病临床医学研究中心、江西省优秀科技创新团队、江西省神经病学研究所、江西省神经内科重点实验室、江西省干细胞重点实验室、江西省卒中中心建设牵头单位的依托科室,是江西省人民医院神经病学疑难病诊治中心。
  江西省人民医院(南昌大学附属人民医院)神经内科现有6个普通病区300张床位及1个神经重症监护室(NICU)22张床位,有150余名医护技研人员。共9名主任医师,9名副主任医师,其中有博导4名(徐仁伵、姚栋元、屈新辉、张昆南)和硕导9名主持和参与国际、国家及省部级课题百余项,开展各种基础和临床研究,在国内外专科杂志发表400余篇论文,多项研究通过成果鉴定,干细胞移植治疗神经系统疾病、多发性硬化、中枢神经系统感染的相关研究分别荣获江西省科技进步二等奖2项、三等奖2项。
  江西省神经病学研究所每年培养博士和硕士研究生约20 余名,博士后科研工作站共接收4 名博士后人员,在研1 人,出站3 人。有5个研究室:①神经干细胞研究室,②神经系统免疫与感染研究室,③神经病理研究室,④神经系统遗传学疾病研究室,⑤神经生化研究室。
  主要开展的研究项目:
  1、神经系统变性疾病:如肌萎缩侧索硬化(ALS)、帕金森病(PD)的发病机制、影像学、基因学、治疗学的实验及临床研究;
  2、睡眠相关性疾病:如睡眠磨牙症的发病机制和治疗、睡眠呼吸暂停的发病机制和治疗、发作性睡病的治疗方法的研究、睡眠异常与帕金森病的关系及帕金森病的治疗等的研究;
  3、脑血管病:如病因学、流行病学、治疗学及缺血性脑血管病介入治疗等方面的实验和临床研究;
  4、神经免疫:如重症肌无力(MG)、多发性硬化(MS)、视神经脊髓炎谱系疾病(NMOSD)、视神经炎(ON)等的发病机制、易感基因、环境因素、检测等相关方面的实验研究和治疗学方面的临床研究;
  5、干细胞治疗:如骨髓干细胞治疗肌萎缩侧索硬化(ALS)、帕金森病(PD)等神经系统变性疾病,多发性硬化 (MS) 等神经免疫、脑血管病、神经系统疑难疾病等实验和临床研究;
  6、中枢神经系统感染性疾病:尤其是结核性脑膜炎的检测等方面的研究;
  7、炎症性和神经性疼痛的研究;
  8、神经肌肉病的病理学、免疫学、治疗学的研究。
  开展临床项目(并开设相关亚专业门诊和亚专业病房
  1、神经介入治疗:动脉溶栓、取栓、颅内外动脉血管成形术和支架置入、动脉瘤栓塞、脑或脊髓动静脉畸形或动静脉瘘栓塞术等治疗技术和相关的临床研究。
  2、神经系统变性疾病的规范诊疗:运动神经元病(MND),如肌萎缩侧索硬化(ALS),帕金森病(PD)、阿尔茨海默病(AD)等诊疗和研究。
  3、神经免疫的规范诊疗和临床研究:重症肌无力(MG)、多发性硬化(MS)、视神经脊髓炎谱系疾病(NMOSD)、急性播散性脑脊髓炎(ADEM)、急性脊髓炎(AM)、急性炎症性脱髓鞘性多发性神经根神经病(AIDP)、慢性炎症性脱髓鞘性多发性神经根神经病(CIDP)、视神经炎(ON)、自身免疫性脑炎等诊疗和研究。
  4、睡眠医学中心:呼吸睡眠监测、磨牙症、发作性睡病、不安腿综合症、焦虑、失眠症等诊疗和研究。
  5、神经感染、神经肌肉病理:脑脊液细胞学、肌肉免疫组化等。
  6、神经重症:血浆置换、床旁血滤、软通道经颅穿刺治疗脑出血等。
  7、神经电生理:动态脑电图、长程脑电监测、针肌电图、单纤维肌电图、诱发电位;重复经颅磁刺激、直流电刺激治疗睡眠障碍、周围性面瘫、认知障碍和运动障碍等技术。
  江西省人民医院(南昌大学附属人民医院)神经内科是我省规模大、设备全、开展新技术多、医疗水平高的知名学科,是神经系统疑难、危重症疾病的诊断、治疗、培训中心。
  今年已发表的论文:
  1. Zhu Yu, Liu Yue, Yang Fang, Chen Wenzhi, Jiang Jianxian, He Pei, Jiang Shishi, Li Menhua, Xu Renshi*. All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice. Mol Neurobiol. 2020, 57(8): 3603-3615.
 
  2. Foo Jia Nee, Chew Elaine Guo Yan, Chung Sun Ju, Peng Rong, Blauwendraat Cornelis, Nalls Mike A, Mok Kin Y, Satake Wataru, Toda Tatsushi, Chao Yinxia, Tan Louis C S, Tandiono Moses, Lian Michelle M, Ng Ebonne Y, Prakash Kumar-M, Au Wing-Lok, Meah Wee-Yang, Mok Shi Qi, Annuar Azlina Ahmad, Chan Anne Y Y, Chen Ling, Chen Yongping, Jeon Beom S, Jiang Lulu, Lim Jia Lun, Lin Juei-Jueng, Liu Chunfeng, Mao Chengjie, Mok Vincent, Pei Zhong, Shang Hui-Fang, Shi Chang-He, Song Kyuyoung, Tan Ai Huey, Wu Yih-Ru, Xu Yu-Ming, Xu Renshi, Yan Yaping, Yang Jing, Zhang BaoRong, Koh Woon-Puay, Lim Shen-Yang, Khor Chiea Chuen, Liu Jianjun, Tan Eng-King. Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. JAMA Neurol. 2020: e200428.
 
  3. Zhou Qi, Zhu Lei, Qiu Weiwen, Liu Yue, Yang Fang, Chen Wenzhi, Xu Renshi*. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1 Mice. Int J Biol Sci. 2020, 16(2): 284-297.
 
  4. Huang G, Zhou X, Yao D*. Report of a case of necrotizing autoimmune myopathy with thymoma-associated myasthenia gravis. Int J Neurosci. 2020 Feb 19:1-4.
 
  5. Xu M, Zhong Z, Zou X, Ouyang Q, Zhang L, Yu B, Yao D*. Eye movements in relation to rhythmic masticatory muscle activities in patients with sleep bruxism. Sleep Med. 2020, 65:36-44.
 
  6. Zhong Z, Xu M, Zou X, Ouyang Q, Zhang L, Yu B, Wang K, Yao D*. Changes in heart rate related to rhythmic masticatory muscle activities and limb movements in patients with sleep bruxism. J Oral Rehabil. 2020, 47(2):170-179.
 
  7. Yao D*, Li J, Yoshida M, Sessle BJ. NMDA and purinergic processes modulate neck muscle activity evoked by noxious stimulation of dura. J Oral Pathol Med. 2020, 49(6):547-554.
 
  8. Yun Yang, Xin-Hui Qu*, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen and Ling-Juan Li. A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features. Frontiers in Cellular and Infection Microbiology. 2020, 9(1):1-10.
 
  9. Zhang P, Cao Y, Chen S, Shao L. Combination of Vinpocetine and Dexamethasone Alleviates Cognitive Impairment in Nasopharyngeal Carcinoma Patients following Radiation Injury. Pharmacology. 2020 Apr 15:1-8.
 
  10. Ping Z, Peng Y, Lang H, Xinyong C, Zhiyi Z, Xiaocheng W, Hong Z, Liang S. Oxidative Stress in Radiation-Induced Cardiotoxicity. Oxid Med Cell Longev. 2020 Mar 1,2020:3579143. 
 
  11. Tang Chunyan, Zhu Lei, Zhou Qi, Li Menghua, Zhu Yu, Xu Zhenzhen, Lu Yi, Xu Renshi*. Altered Features of Vimentin-containing Cells in Cerebrum of Tg(SOD1*G93A)1Gur Mice: A Preliminary Study on Cerebrum Endogenous Neural Precursor Cells in Amyotrophic Lateral Sclerosis. Int J Biol Sci. 2019, 15(13): 2830-2843.
 
  12. Han K, Wang C, Zhong Z, Xu M, Zou X, Yu B, Wang K, Yao D*. Characterization of the relationships between rhythmic masticatory muscle activities and limb movements in patients with sleep bruxism. J Oral Rehabil. 2019, 46(5): 399-408.
 
  13. Lu J, Zhang Y, Han K, Wang C, Zhong Z, Xu M, Zou X, Yu B, Yao D*. Heart rate changes associated with rhythmic masticatory muscle activities and limb movements in sleep bruxers: Preliminary findings. Cranio. 2019, Feb 16:1-11.
 
  14. Shi-Min Liu, Xian-Min Cao, Xin-Hui Qu*, Wen Cai, Fan Hu, Wen-Feng Cao, Lin-Feng Wu and Xiao-Mu Wu. Effects of remote ischemic preconditioning on astrocyte proliferation and glial scars after cerebral infarction. European Journal of Inflammation. 2019;17:1-6.
 
  15. Yun Yang, Xiaomu Wu, Xinhui Qu, Xinrong Wang, Chaoqun Luo, Lingjuan Li, Kunnan Zhang*. The Effect of Triggering Receptor Expressed by Myeloid Cells 2 Modified Bone Marrow Mesenchymal Stem Cells on Alzheimer's Disease-Mouse Model. Annals of Clinical & Laboratory Science. 2019, 49(1): 23-30.
 
  16. Xin-Hui Qu*, Wan-Song Wang, Yun Yang, Shi-Min Liu, Ling-Feng Wu, Chen Xie, Xiao-Yan Yang, Yan He, Xiao-Mu Wu. A Study on Acute Ischemia-Reperfusion Models in Rats Treated by Bone Mesenchymal Stem Cells Grafting via Arteries and Veins. Journal of Hard Tissue Biology. 2019, 28 (4): 323-328.
 
  17. Min Yuan, Xu-Fang Xie, Wen-Feng Cao, Ying-Qiong Xiong, Ling-Feng Wu, Huang-Yan Zhou and Xiao-Mu Wu, 'Proton Pump Inhibitors and the Risk of Dementia: Is There a Link?', MEDICAL PRINCIPLES AND PRACTICE, 27 (2019), 585.
 
  18. Zhang J, Huang P, Wu C, Liang H, Li Y, Zhu L, Lu Y, Tang C, Xu R. Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice. Int J Biol Sci. 2018, 14(10):1306-1320.
 
  19. Liu Y, Zhu H, Zhang Z, Tu C, Yao D et al. Effects of a single transient transfection of Ten-eleven translocation 1 catalytic domain on hepatocellular carcinoma. PLOS one. 2018, 14, 13(12):e0207139.
 
  20. Yao D*, Sessle BJ. Face sensorimotor cortex undergoes neuroplastic changes in a rat model of trigeminal neuropathic pain. Exp Brain Res. 2018, 236(5): 1357-1368.
 
  21. An WenXin-Hui Qu*Kun-Nan ZhangEr-Ling LengYue RenXiao-Mu Wu. Evaluation of Interferon-Gamma Release Assays in Extrasanguinous Body Fluids for Diagnosing Tuberculosis: A Systematic Review and Meta-analysis. Life Sciences. 2018, 197:140–146.
 
  22. Min Yuan, Wen-Feng Cao, Xu-Fang Xie, Huang-Yan Zhou, Xiao-Mu Wu. Relationship of atopic dermatitis with stroke and myocardial infarction: A meta-analysis. Medicine. (2018), 97(49),e13512.
 
  23. Liu SYCao WF*, Wu LF, Xiang ZB, Liu SM, Liu HY, Pan Y, Nie F, Wu XM, Xie XF. Effect of glycated hemoglobin index and mean arterial pressure on acute ischemic stroke prognosis after intravenous thrombolysis with recombinant tissue plasminogen activator. Medicine. 2018, 97(49), e13216.
 
  24. Shiying L, Xinhui Q, Guanghua J, Feng N, Feng L, Shumei C, Fan H. Puerarin promoted proliferation and differentiation of dopamine-producing cells in Parkinson’s animal models. Biomed Pharmacother. 2018, 106:1236-1242.
 
  25. Ping Z, Xiaomu W, Xufang X, Liang S. Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients. Neurol Sci, 2018 Oct 12.
 
  26. Liang S , Xinyong C , Hongmin Z , Jing W , Lang H , Ping Z . TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. Toxicology letters. 2018 Oct; 295205-211.
 
  27. Jian Hu, Shiying Liu, Yuanzhi Qiu. The Role of Gap Junction in Regulating Vascular Function and Its Relationship with Hypertension. International Journal of Clinical and Experimental Medical Sciences. 2018, 4(3): 46-50.
 
  28. Ping Z, Xiaomu W, Xufang X, Wenfeng C, Liang S, Tao W. GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease. Neuroscience letters. 2018, 685:55-62.
   
  29. Zhang PShao LMa J. Toll-Like Receptors 2 and 4 Predict New-Onset Atrial Fibrillation in Acute Myocardial Infarction Patients. International Heart Journal. 2018, 59(1):64-70.
 
  30. Min Yuan and Qiu-Gen Li, 'Lung Cancer and Risk of Cardiovascular Disease: A Meta-analysis of Cohort Studies', JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 32 (2018), e25-7.
 
  31. Min Yuan, Wen-Feng Cao, Xu-Fang Xie, Huang-Yan Zhou and Xiao-Mu Wu, 'Relationship of atopic dermatitis with stroke and myocardial infarction', MEDICINE, 97 (2018), e13512.
  
  32. Zhang J, Liang H, Zhu L, Gan W, Tang C, Li J, Xu R. Expression and Distribution of Arylsulfatase B are Closely Associated with Neuron Death in SOD1 G93A Transgenic Mice. Mol Neurobiol. 2017, 55(2):1323-1337.
 
  33. Liang H, Wu C, Deng Y, Zhu L, Zhang J, Gan W, Tang C, Xu R. Aldehyde Dehydrogenases 1A2 Expression and Distribution are Potentially Associated with Neuron Death in Spinal Cord of Tg(SOD1*G93A)1Gur Mice. Int J Biol Sci. 2017, 13(5):574-587.
 
  34. Zheng Z, Lit Wan DW, Arendt-Nielsen L, Yao D, Iversen G, Changli Xue C, Wang K. Being adaptive to pain enhances sham acupuncture analgesia: a cross-over healthy human study. Journal of Acupuncture and Meridian Studies. 2017, 10(6):385-395.
 
  35. Sessle BJ, Adachi K, Yao D, Suzuki Y, Lavigne GJ. Orofacial pain and sleep. Contemporary Oral Medicine. Camile Farah, Ramesh Balasubramaniam and Michael McCullough (eds). Springer International Publishing, ISBN-10: 3319723022, ISBN-13: 978-3319723020. 2017, pp 1-27.
 
  36. Zhang Y, Lu J, Wang Z, Zhong Z, Xu M, Zou X, Yu B, Yao D*. Companion of oral movements with limb movements in patients with sleep bruxism: preliminary findings. Sleep Med. 2017, 36:156-164.
 
  37. Tang X, Li J, Jiang T, Han SH, Yao D. Experimental occlusal disharmony-A promoting factor for anxiety in rats under chronic psychological stress. Prog Neuropsychopharmacol Biol Psychiatry. 2017, 75:165-175.
 
  38. Liang SPing Z*Ge J. Coenzyme Q10 Regulates Antioxidative Stress and Autophagy in Acute Myocardial Ischemia-Reperfusion Injury. Oxidative Medicine and Cellular Longevity. 2017, 2017:9863181.
 
  39. Ping ZAiqun MJiwu LLiang S. TNF Receptor 1/2 Predict Heart Failure Risk in Type 2 Diabetes Mellitus Patients. International Heart Journal. 2017, 58(2): 245-249.
 
  40. Lingjuan Li, Mingyue Wang, Zhujun Mei, Wenfeng Cao, Yun Yang, Yanmei Wang, An Wen. lncRNAs HIF1A-AS2 facilitates the up-regulation of HIF-1α by sponging to miR-153-3p, whereby promoting angiogenesis in HUVECs in hypoxia. Biomedicine & Pharmacotherapy. 2017, 96(0):165-172.
 
  41. Yue Ren, Etsuko Sekine-Kondo, Risa Shibata, Megumi Kato-Itoh, Ayumi Umino, Ayaka Yanagida, Masashi Satoh, Komaki Inoue, Tomoyuki Yamaguchi, Keiichi Mochida, Susumu Nakae, Luc Van Kaer, Kazuya Iwabuchi, Hiromitsu Nakauchi, Hiroshi Watarai. A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease. Scientific Reports. 2017,7(1):12765.
 
  42. Tang C, Zhu L, Gan W, Liang H, Li J, Zhang J, Zhang X, Lu Y, Xu R*. Distributed Features of Vimentin-Containing Neural Precursor Cells in Olfactory Bulb of SOD1G93A Transgenic Mice: a Study about Resource of Endogenous Neural Stem Cells. Int J Biol Sci. 2016, 12(12):1405-1414.
 
  43. Li J, Lu Y, Liang H, Tang C, Zhu L, Zhang J, Xu R*. Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration. Int J Biol Sci. 2016, 12(10):1181-1190.
 
  44. Lu Y, Tang C, Zhu L, Li J, Liang H, Zhang J, Xu R*. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis. Int J Biol Sci. 2016,12(9):1140-1149.
 
  45. Deng L, Huo L, Zhang J, Tang X, Cheng Z, Li G, Fang X, Xu J, Zhang X, Xu R. Polymorphism of rs3737597 in DISC1 Gene on Chromosome 1q42.2 in sALS Patients: a Chinese Han Population Case-Control Study. Mol Neurobiol. 2016, 54(5):1-18.
 
  46. Shao L, Ma A, Figtree G, Zhang P. Combination therapy with coenzyme Q10 and trimetazidine in acute viral myocarditis patients. Journal of Cardiovascular Pharmacology. 2016, 68(2):150-154.
  
  47. Liang S, Aiqun M, Jiwu L, Ping Z. TLR3 and TLR4 as potential clinical biomarkers for in-stent restenosis in drug-eluting stents patients. Immunologic Research. 2016, 64(2):424-430.
 
  48. M. Yuan, H. Y. Zhou, X. L. Xiao, Z. Q. Wang, Yao-Zhi and X. P. Yin, 'Inflammatory bowel disease and risk of stroke: A meta-analysis of cohort studies', INTERNATIONAL JOURNAL OF CARDIOLOGY, 202 (2016), 106-9.
 
  49. Min Yuan, Huang-yan Zhou, Zhi-long Xiao, Wei Wang, Xue-li Li, Shen-jian Chen, Xiao-ping Yin and Li-jun Xu, 'Efficacy and Safety of Gabapentin vs. Carbamazepine in the Treatment of Trigeminal Neuralgia: A Meta-Analysis', Pain Practice, 16 (2016), 1083-91.
 
  50. Min Yuan, Weiping Chen, Huangyan Zhou, Zhilong Xiao, Wei Wang, Weidong Wang, Xiaoping Yin and Lijun Xu, 'Kennedy Disease Misdiagnosed as Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Case Report', MEDICAL PRINCIPLES AND PRACTICE, 25 (2016), 286-9.
 
  51. Min Yuan, Lijun Xu and Xiaoping Yin, 'Uric Acid and the Risk of Alzheimer’s Disease', American Journal of Alzheimer's Disease & Other Dementiasr, 31 (2016), 294-5.
 
  52. Huangyan Zhou, Min Yuan, Qiongfang Yu, Xiaoyan Zhou, Weiping Min and Dian Gao, 'Autophagy regulation and its role in gastric cancer and colorectal cancer', Cancer Biomarkers, 17 (2016), 1-10.
 
  53. Zhou Y, Lu Y, Fang X, Zhang J, Li J, Li S, Deng X, Yu Y, Xu R. An Astrocyte Regenerative Response from Vimentin-Containing Cells in the Spinal Cord of Amyotrophic Lateral Sclerosis's Disease-Like Transgenic (G93A SOD1) Mice. Neurodegener Dis. 2015, 15:1-12.
 
  54. Yao D*, Yoshida M, Sessle BJ. Dura-evoked neck muscle activity involves purinergic and N-methyl-D-aspartate receptor mechanisms. Neuroreport. 2015, 26 (18):1155-60.
 
  55. Liang S, Aiqun M, Figtree G, Ping Z.GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury. International Journal Of Biological Macromolecules. 2015, 81:375-386.
 
  56. Liu L, Xiong N, Zhang P, Chen C, Huang J, Zhang G, Xu X, Shen Y, Lin Z, Wang T. Genetic variants in GAPDH confer susceptibility to sporadic Parkinson's disease in a Chinese Han population. PLoS One. 2015, 10(8):e0135425.
 
  57. Liang S, Figtree G, Aiqun M, Ping Z. GAPDH-knockdown reduce rotenone- induced H9C2 cells death via autophagy and anti-oxidative stress pathway. Toxicology letters. 2015, 234(3):162-71.
 
  58. Zhang P, Cao F, Xiong N, Huang J, Wang T, Shao L.flg2 as a potential biomarker of acute cerebral ischemic-reperfusion injury. Microvascular Research. 2015, 99: 36-42.
 
  59. Min Yuan, Zhi-qiang Liu, Zhi-qiang Wang, Bin Li, Li-jun Xu and Xin-lan Xiao, 'High-resolution MR imaging of the arterial wall in moyamoya disease', NEUROSCIENCE LETTERS, 584 (2015), 77-82.
 
  60. Min Yuan, Shen-jian Chen, Xue-li Li and Li-jun Xu, 'Blood Pressure and the Risk of Alzheimer’s Disease', American Journal of Alzheimer's Disease & Other Dementiasr, 31 (2015), 97-8.
 
  61. Xie T, Deng L, Mei P, Zhou Y, Wang B, Zhang J, Lin J, Wei Y, Zhang X, Xu R. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han population. Neurobiol Aging. 2014, 35(7):1778.e9-1778.e23.
 
  62. Zhang P, Liu L, Huang J, Shao L, Wang H, Xiong N, Wang T. Non-SMC condensin I complex, subunit D2 gene polymorphisms are associated with Parkinson's disease: a Han Chinese study. Genome. 2014, 57(5):253-257.
 
  63. Zheng Z, Wang K, Yao D, Xue CC, Arendt-Nielsen L.  Adaptability to pain is associated with potency of local pain inhibition, but not conditioned pain modulation: A healthy human study. Pain. 2014, 155(5):968-976. 
 
  64. Lingfeng Wu, Kunnan Zhang, Guozhu Hu, Haiyu Yan, Chen Xie, Xiaomu Wu. Inflammatory response and neuronal necrosis in rats with cerebral ischemia. Neural Regen Res. 2014 ,9(19):1753-1762.
 
  65. Yao D, Lavigne GJ, Lee J-C, Adachi K, Sessle BJ. Jaw-opening reflex and corticobulbar motor excitability changes during quiet sleep in non-human primates. Sleep. 2013, 36: 269-280. 
 
  66. Huynh N, Lavigne, GJ, Okura K, Yao D, Adachi K. Sleep bruxism: an annoying motor manifestation during sleep under brainstem neuronal control. In: Handbook of Clinical Neurology, the third series, Section on Sleep Disorders. P. Montagna and S. Chokroverty Section. Eds, Elsevier, 2011, 99:901-911.
 
  67. Avivi-Arber L, Lee JC, Yao D, Adachi K, Sessle BJ. Neuroplasticity of face sensorimotor cortex and implications for control of orofacial movements. Japanese Dental Science Review. 2010, 46 (2): 132-142. 
 
  获省科技进步奖:
  1、人骨髓间充质干细胞向不同神经元分化研究,2010年江西省科技进步二等奖;
  2、多发性硬化的临床与分子遗传学特点研究与应用,2011年江西省科技进步三等奖;
  3、骨髓间充质干细胞治疗神经系统难治性疾病的基础与临床研究,2018年江西省科技进步二等奖;
  4、结核性脑膜炎早期快速诊断方法的建立和应用,2019年江西省科技进步三等奖。


作为评估中国医院学科建设水平的标杆之一,复旦版中国医院排行榜,在2020年12月份揭榜。江西省人民医院在2019年度华东区神经内科声誉排行榜上获提名。同时神经内科在医信天下2020中国医院影响力神经内科排行榜同等53名。



  复旦大学医院管理研究所在上海颁布《2019年度中国医院排行榜》、《2019年度中国医院专科声誉排行榜》和《2019年中国医院专科综合排行榜》,这是复旦大学医院管理研究所作为独立第三方开展的公益性学科评估项目,已是复旦版中国医院排行榜连续第十一年发布。
  在成为中国医院学科建设的一个标杆同时,该榜单也常常被作为大众疑难杂症寻找心中好医院的重要参考。根据排行榜,该榜单由复旦大学医院管理研究所发布,借鉴美国“最佳医院排行榜”的评价方法,坚持以临床学科水平、专科声誉为核心,兼顾当年的科研产出。由于评价方法的科学性,排行榜的评选结果亦得到医疗行业广泛认可。
  我院神经内科在全国神经病学中占有一席之地,离不开江西省卫健委的正确指引和院领导的大力支持。学科建设是医院发展的重中之重,是医院品牌、声誉、地位的基石,是医院增进绩效、合理分配、吸引人才的基础,也是医院加强管理、提高质量、发展医学的抓手。
 
  江西省人民医院神经内科简介
 
  江西省人民医院(南昌大学附属人民医院)神经内科是江西省唯一卫生部认定的国家临床重点专科(神经内科专业),国家高级卒中中心,国家卫健委指定的脑卒中筛查与防治基地,国家卫健委指定的临床路径试点单位,国家住院医师规范化培训神经内科专业基地,国家药物临床实验机构,国家神经变性病联盟高级中心,华南神经系统线粒体病协作联盟,中华医学会神经病学分会委员单位,江西省医学会神经病学分会主委单位,江西省保健学会神经病学分会和睡眠医学分会主委单位。是江西省神经内科专业质量控制中心、江西省神经系统疾病临床医学研究中心、江西省优秀科技创新团队、江西省神经病学研究所、江西省神经内科重点实验室、江西省干细胞重点实验室、江西省卒中中心建设牵头单位的依托科室,是江西省人民医院神经病学疑难病诊治中心。
  江西省人民医院(南昌大学附属人民医院)神经内科现有6个普通病区300张床位及1个神经重症监护室(NICU)22张床位,有150余名医护技研人员。共9名主任医师,9名副主任医师,其中有博导4名(徐仁伵、姚栋元、屈新辉、张昆南)和硕导9名主持和参与国际、国家及省部级课题百余项,开展各种基础和临床研究,在国内外专科杂志发表400余篇论文,多项研究通过成果鉴定,干细胞移植治疗神经系统疾病、多发性硬化、中枢神经系统感染的相关研究分别荣获江西省科技进步二等奖2项、三等奖2项。
  江西省神经病学研究所每年培养博士和硕士研究生约20 余名,博士后科研工作站共接收4 名博士后人员,在研1 人,出站3 人。有5个研究室:①神经干细胞研究室,②神经系统免疫与感染研究室,③神经病理研究室,④神经系统遗传学疾病研究室,⑤神经生化研究室。
  主要开展的研究项目:
  1、神经系统变性疾病:如肌萎缩侧索硬化(ALS)、帕金森病(PD)的发病机制、影像学、基因学、治疗学的实验及临床研究;
  2、睡眠相关性疾病:如睡眠磨牙症的发病机制和治疗、睡眠呼吸暂停的发病机制和治疗、发作性睡病的治疗方法的研究、睡眠异常与帕金森病的关系及帕金森病的治疗等的研究;
  3、脑血管病:如病因学、流行病学、治疗学及缺血性脑血管病介入治疗等方面的实验和临床研究;
  4、神经免疫:如重症肌无力(MG)、多发性硬化(MS)、视神经脊髓炎谱系疾病(NMOSD)、视神经炎(ON)等的发病机制、易感基因、环境因素、检测等相关方面的实验研究和治疗学方面的临床研究;
  5、干细胞治疗:如骨髓干细胞治疗肌萎缩侧索硬化(ALS)、帕金森病(PD)等神经系统变性疾病,多发性硬化 (MS) 等神经免疫、脑血管病、神经系统疑难疾病等实验和临床研究;
  6、中枢神经系统感染性疾病:尤其是结核性脑膜炎的检测等方面的研究;
  7、炎症性和神经性疼痛的研究;
  8、神经肌肉病的病理学、免疫学、治疗学的研究。
  开展临床项目(并开设相关亚专业门诊和亚专业病房
  1、神经介入治疗:动脉溶栓、取栓、颅内外动脉血管成形术和支架置入、动脉瘤栓塞、脑或脊髓动静脉畸形或动静脉瘘栓塞术等治疗技术和相关的临床研究。
  2、神经系统变性疾病的规范诊疗:运动神经元病(MND),如肌萎缩侧索硬化(ALS),帕金森病(PD)、阿尔茨海默病(AD)等诊疗和研究。
  3、神经免疫的规范诊疗和临床研究:重症肌无力(MG)、多发性硬化(MS)、视神经脊髓炎谱系疾病(NMOSD)、急性播散性脑脊髓炎(ADEM)、急性脊髓炎(AM)、急性炎症性脱髓鞘性多发性神经根神经病(AIDP)、慢性炎症性脱髓鞘性多发性神经根神经病(CIDP)、视神经炎(ON)、自身免疫性脑炎等诊疗和研究。
  4、睡眠医学中心:呼吸睡眠监测、磨牙症、发作性睡病、不安腿综合症、焦虑、失眠症等诊疗和研究。
  5、神经感染、神经肌肉病理:脑脊液细胞学、肌肉免疫组化等。
  6、神经重症:血浆置换、床旁血滤、软通道经颅穿刺治疗脑出血等。
  7、神经电生理:动态脑电图、长程脑电监测、针肌电图、单纤维肌电图、诱发电位;重复经颅磁刺激、直流电刺激治疗睡眠障碍、周围性面瘫、认知障碍和运动障碍等技术。
  江西省人民医院(南昌大学附属人民医院)神经内科是我省规模大、设备全、开展新技术多、医疗水平高的知名学科,是神经系统疑难、危重症疾病的诊断、治疗、培训中心。
  今年已发表的论文:
  1. Zhu Yu, Liu Yue, Yang Fang, Chen Wenzhi, Jiang Jianxian, He Pei, Jiang Shishi, Li Menhua, Xu Renshi*. All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice. Mol Neurobiol. 2020, 57(8): 3603-3615.
 
  2. Foo Jia Nee, Chew Elaine Guo Yan, Chung Sun Ju, Peng Rong, Blauwendraat Cornelis, Nalls Mike A, Mok Kin Y, Satake Wataru, Toda Tatsushi, Chao Yinxia, Tan Louis C S, Tandiono Moses, Lian Michelle M, Ng Ebonne Y, Prakash Kumar-M, Au Wing-Lok, Meah Wee-Yang, Mok Shi Qi, Annuar Azlina Ahmad, Chan Anne Y Y, Chen Ling, Chen Yongping, Jeon Beom S, Jiang Lulu, Lim Jia Lun, Lin Juei-Jueng, Liu Chunfeng, Mao Chengjie, Mok Vincent, Pei Zhong, Shang Hui-Fang, Shi Chang-He, Song Kyuyoung, Tan Ai Huey, Wu Yih-Ru, Xu Yu-Ming, Xu Renshi, Yan Yaping, Yang Jing, Zhang BaoRong, Koh Woon-Puay, Lim Shen-Yang, Khor Chiea Chuen, Liu Jianjun, Tan Eng-King. Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. JAMA Neurol. 2020: e200428.
 
  3. Zhou Qi, Zhu Lei, Qiu Weiwen, Liu Yue, Yang Fang, Chen Wenzhi, Xu Renshi*. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1 Mice. Int J Biol Sci. 2020, 16(2): 284-297.
 
  4. Huang G, Zhou X, Yao D*. Report of a case of necrotizing autoimmune myopathy with thymoma-associated myasthenia gravis. Int J Neurosci. 2020 Feb 19:1-4.
 
  5. Xu M, Zhong Z, Zou X, Ouyang Q, Zhang L, Yu B, Yao D*. Eye movements in relation to rhythmic masticatory muscle activities in patients with sleep bruxism. Sleep Med. 2020, 65:36-44.
 
  6. Zhong Z, Xu M, Zou X, Ouyang Q, Zhang L, Yu B, Wang K, Yao D*. Changes in heart rate related to rhythmic masticatory muscle activities and limb movements in patients with sleep bruxism. J Oral Rehabil. 2020, 47(2):170-179.
 
  7. Yao D*, Li J, Yoshida M, Sessle BJ. NMDA and purinergic processes modulate neck muscle activity evoked by noxious stimulation of dura. J Oral Pathol Med. 2020, 49(6):547-554.
 
  8. Yun Yang, Xin-Hui Qu*, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen and Ling-Juan Li. A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features. Frontiers in Cellular and Infection Microbiology. 2020, 9(1):1-10.
 
  9. Zhang P, Cao Y, Chen S, Shao L. Combination of Vinpocetine and Dexamethasone Alleviates Cognitive Impairment in Nasopharyngeal Carcinoma Patients following Radiation Injury. Pharmacology. 2020 Apr 15:1-8.
 
  10. Ping Z, Peng Y, Lang H, Xinyong C, Zhiyi Z, Xiaocheng W, Hong Z, Liang S. Oxidative Stress in Radiation-Induced Cardiotoxicity. Oxid Med Cell Longev. 2020 Mar 1,2020:3579143. 
 
  11. Tang Chunyan, Zhu Lei, Zhou Qi, Li Menghua, Zhu Yu, Xu Zhenzhen, Lu Yi, Xu Renshi*. Altered Features of Vimentin-containing Cells in Cerebrum of Tg(SOD1*G93A)1Gur Mice: A Preliminary Study on Cerebrum Endogenous Neural Precursor Cells in Amyotrophic Lateral Sclerosis. Int J Biol Sci. 2019, 15(13): 2830-2843.
 
  12. Han K, Wang C, Zhong Z, Xu M, Zou X, Yu B, Wang K, Yao D*. Characterization of the relationships between rhythmic masticatory muscle activities and limb movements in patients with sleep bruxism. J Oral Rehabil. 2019, 46(5): 399-408.
 
  13. Lu J, Zhang Y, Han K, Wang C, Zhong Z, Xu M, Zou X, Yu B, Yao D*. Heart rate changes associated with rhythmic masticatory muscle activities and limb movements in sleep bruxers: Preliminary findings. Cranio. 2019, Feb 16:1-11.
 
  14. Shi-Min Liu, Xian-Min Cao, Xin-Hui Qu*, Wen Cai, Fan Hu, Wen-Feng Cao, Lin-Feng Wu and Xiao-Mu Wu. Effects of remote ischemic preconditioning on astrocyte proliferation and glial scars after cerebral infarction. European Journal of Inflammation. 2019;17:1-6.
 
  15. Yun Yang, Xiaomu Wu, Xinhui Qu, Xinrong Wang, Chaoqun Luo, Lingjuan Li, Kunnan Zhang*. The Effect of Triggering Receptor Expressed by Myeloid Cells 2 Modified Bone Marrow Mesenchymal Stem Cells on Alzheimer's Disease-Mouse Model. Annals of Clinical & Laboratory Science. 2019, 49(1): 23-30.
 
  16. Xin-Hui Qu*, Wan-Song Wang, Yun Yang, Shi-Min Liu, Ling-Feng Wu, Chen Xie, Xiao-Yan Yang, Yan He, Xiao-Mu Wu. A Study on Acute Ischemia-Reperfusion Models in Rats Treated by Bone Mesenchymal Stem Cells Grafting via Arteries and Veins. Journal of Hard Tissue Biology. 2019, 28 (4): 323-328.
 
  17. Min Yuan, Xu-Fang Xie, Wen-Feng Cao, Ying-Qiong Xiong, Ling-Feng Wu, Huang-Yan Zhou and Xiao-Mu Wu, 'Proton Pump Inhibitors and the Risk of Dementia: Is There a Link?', MEDICAL PRINCIPLES AND PRACTICE, 27 (2019), 585.
 
  18. Zhang J, Huang P, Wu C, Liang H, Li Y, Zhu L, Lu Y, Tang C, Xu R. Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice. Int J Biol Sci. 2018, 14(10):1306-1320.
 
  19. Liu Y, Zhu H, Zhang Z, Tu C, Yao D et al. Effects of a single transient transfection of Ten-eleven translocation 1 catalytic domain on hepatocellular carcinoma. PLOS one. 2018, 14, 13(12):e0207139.
 
  20. Yao D*, Sessle BJ. Face sensorimotor cortex undergoes neuroplastic changes in a rat model of trigeminal neuropathic pain. Exp Brain Res. 2018, 236(5): 1357-1368.
 
  21. An WenXin-Hui Qu*Kun-Nan ZhangEr-Ling LengYue RenXiao-Mu Wu. Evaluation of Interferon-Gamma Release Assays in Extrasanguinous Body Fluids for Diagnosing Tuberculosis: A Systematic Review and Meta-analysis. Life Sciences. 2018, 197:140–146.
 
  22. Min Yuan, Wen-Feng Cao, Xu-Fang Xie, Huang-Yan Zhou, Xiao-Mu Wu. Relationship of atopic dermatitis with stroke and myocardial infarction: A meta-analysis. Medicine. (2018), 97(49),e13512.
 
  23. Liu SYCao WF*, Wu LF, Xiang ZB, Liu SM, Liu HY, Pan Y, Nie F, Wu XM, Xie XF. Effect of glycated hemoglobin index and mean arterial pressure on acute ischemic stroke prognosis after intravenous thrombolysis with recombinant tissue plasminogen activator. Medicine. 2018, 97(49), e13216.
 
  24. Shiying L, Xinhui Q, Guanghua J, Feng N, Feng L, Shumei C, Fan H. Puerarin promoted proliferation and differentiation of dopamine-producing cells in Parkinson’s animal models. Biomed Pharmacother. 2018, 106:1236-1242.
 
  25. Ping Z, Xiaomu W, Xufang X, Liang S. Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients. Neurol Sci, 2018 Oct 12.
 
  26. Liang S , Xinyong C , Hongmin Z , Jing W , Lang H , Ping Z . TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. Toxicology letters. 2018 Oct; 295205-211.
 
  27. Jian Hu, Shiying Liu, Yuanzhi Qiu. The Role of Gap Junction in Regulating Vascular Function and Its Relationship with Hypertension. International Journal of Clinical and Experimental Medical Sciences. 2018, 4(3): 46-50.
 
  28. Ping Z, Xiaomu W, Xufang X, Wenfeng C, Liang S, Tao W. GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease. Neuroscience letters. 2018, 685:55-62.
   
  29. Zhang PShao LMa J. Toll-Like Receptors 2 and 4 Predict New-Onset Atrial Fibrillation in Acute Myocardial Infarction Patients. International Heart Journal. 2018, 59(1):64-70.
 
  30. Min Yuan and Qiu-Gen Li, 'Lung Cancer and Risk of Cardiovascular Disease: A Meta-analysis of Cohort Studies', JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 32 (2018), e25-7.
 
  31. Min Yuan, Wen-Feng Cao, Xu-Fang Xie, Huang-Yan Zhou and Xiao-Mu Wu, 'Relationship of atopic dermatitis with stroke and myocardial infarction', MEDICINE, 97 (2018), e13512.
  
  32. Zhang J, Liang H, Zhu L, Gan W, Tang C, Li J, Xu R. Expression and Distribution of Arylsulfatase B are Closely Associated with Neuron Death in SOD1 G93A Transgenic Mice. Mol Neurobiol. 2017, 55(2):1323-1337.
 
  33. Liang H, Wu C, Deng Y, Zhu L, Zhang J, Gan W, Tang C, Xu R. Aldehyde Dehydrogenases 1A2 Expression and Distribution are Potentially Associated with Neuron Death in Spinal Cord of Tg(SOD1*G93A)1Gur Mice. Int J Biol Sci. 2017, 13(5):574-587.
 
  34. Zheng Z, Lit Wan DW, Arendt-Nielsen L, Yao D, Iversen G, Changli Xue C, Wang K. Being adaptive to pain enhances sham acupuncture analgesia: a cross-over healthy human study. Journal of Acupuncture and Meridian Studies. 2017, 10(6):385-395.
 
  35. Sessle BJ, Adachi K, Yao D, Suzuki Y, Lavigne GJ. Orofacial pain and sleep. Contemporary Oral Medicine. Camile Farah, Ramesh Balasubramaniam and Michael McCullough (eds). Springer International Publishing, ISBN-10: 3319723022, ISBN-13: 978-3319723020. 2017, pp 1-27.
 
  36. Zhang Y, Lu J, Wang Z, Zhong Z, Xu M, Zou X, Yu B, Yao D*. Companion of oral movements with limb movements in patients with sleep bruxism: preliminary findings. Sleep Med. 2017, 36:156-164.
 
  37. Tang X, Li J, Jiang T, Han SH, Yao D. Experimental occlusal disharmony-A promoting factor for anxiety in rats under chronic psychological stress. Prog Neuropsychopharmacol Biol Psychiatry. 2017, 75:165-175.
 
  38. Liang SPing Z*Ge J. Coenzyme Q10 Regulates Antioxidative Stress and Autophagy in Acute Myocardial Ischemia-Reperfusion Injury. Oxidative Medicine and Cellular Longevity. 2017, 2017:9863181.
 
  39. Ping ZAiqun MJiwu LLiang S. TNF Receptor 1/2 Predict Heart Failure Risk in Type 2 Diabetes Mellitus Patients. International Heart Journal. 2017, 58(2): 245-249.
 
  40. Lingjuan Li, Mingyue Wang, Zhujun Mei, Wenfeng Cao, Yun Yang, Yanmei Wang, An Wen. lncRNAs HIF1A-AS2 facilitates the up-regulation of HIF-1α by sponging to miR-153-3p, whereby promoting angiogenesis in HUVECs in hypoxia. Biomedicine & Pharmacotherapy. 2017, 96(0):165-172.
 
  41. Yue Ren, Etsuko Sekine-Kondo, Risa Shibata, Megumi Kato-Itoh, Ayumi Umino, Ayaka Yanagida, Masashi Satoh, Komaki Inoue, Tomoyuki Yamaguchi, Keiichi Mochida, Susumu Nakae, Luc Van Kaer, Kazuya Iwabuchi, Hiromitsu Nakauchi, Hiroshi Watarai. A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease. Scientific Reports. 2017,7(1):12765.
 
  42. Tang C, Zhu L, Gan W, Liang H, Li J, Zhang J, Zhang X, Lu Y, Xu R*. Distributed Features of Vimentin-Containing Neural Precursor Cells in Olfactory Bulb of SOD1G93A Transgenic Mice: a Study about Resource of Endogenous Neural Stem Cells. Int J Biol Sci. 2016, 12(12):1405-1414.
 
  43. Li J, Lu Y, Liang H, Tang C, Zhu L, Zhang J, Xu R*. Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration. Int J Biol Sci. 2016, 12(10):1181-1190.
 
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  获省科技进步奖:
  1、人骨髓间充质干细胞向不同神经元分化研究,2010年江西省科技进步二等奖;
  2、多发性硬化的临床与分子遗传学特点研究与应用,2011年江西省科技进步三等奖;
  3、骨髓间充质干细胞治疗神经系统难治性疾病的基础与临床研究,2018年江西省科技进步二等奖;
  4、结核性脑膜炎早期快速诊断方法的建立和应用,2019年江西省科技进步三等奖。



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